An ESIPT based naphthalimide chemosensor for visualizing endogenous ONOO− in living cells
نویسندگان
چکیده
منابع مشابه
An Aldol Reaction-Based Iridium(III) Chemosensor for the Visualization of Proline in Living Cells
A long-lived aldol reaction-based iridium(III) chemosensor [Ir(ppy)2(5-CHOphen)]PF6 (1, where ppy = 2-phenylpyridine and 5-CHOphen = 1,10-phenanthroline-5-carbaldehyde) for proline detection has been synthesized. The iridium(III) complex 1, incorporating an aldehyde group in N^N donor ligand, can take part in aldol reaction with acetone mediated by proline. The transformation of the sp2-hybridi...
متن کاملRecombinant Probes for Visualizing Endogenous Synaptic Proteins in Living Neurons
The ability to visualize endogenous proteins in living neurons provides a powerful means to interrogate neuronal structure and function. Here we generate recombinant antibody-like proteins, termed Fibronectin intrabodies generated with mRNA display (FingRs), that bind endogenous neuronal proteins PSD-95 and Gephyrin with high affinity and that, when fused to GFP, allow excitatory and inhibitory...
متن کاملFlavone-Based ESIPT Ratiometric Chemodosimeter for Detection of Cysteine in Living Cells
We have designed and synthesized a novel ratiometric fluorescent chemodosimeter MHF-based ESIPT process for specific detection of cysteine among the biological thiols. The probe MHF shows very weak blue fluorescence under UV excitation. Upon addition of cysteine (Cys), the reaction of Cys with MHF induces acrylate hydrolysis, thereby enabling the ESIPT process to shift the weak blue emission to...
متن کاملNaphthalimide-based fluorescent probe for selectively and specifically detecting glutathione in the lysosomes of living cells.
A novel naphthalimide-based fluorescent probe employing a sulfonamide unit as a thiol-responsive group is reported. It is capable of efficiently distinguishing GSH from cysteine and homocysteine. Bioimaging shows that it has high selectivity in living cells and can visualize the level of GSH in lysosomes. It is worth mentioning that different groups on the imide unit can affect the selectivity ...
متن کاملA naphthalimide based chemosensor for Zn2+, pyrophosphate and H2O2: sequential logic operations at the molecular level.
A naphthalimide based fluorescent probe has been synthesized which shows ratiometric fluorescence response towards Zn(2+) ions and the in situ prepared -Zn(2+) complex was used for the detection of pyrophosphate and hydrogen peroxide which mimics the functions of sequential logic circuits at the molecular level.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: RSC Advances
سال: 2018
ISSN: 2046-2069
DOI: 10.1039/c7ra11774d